Изоляция и характеристика основных фитохимических соединений из Clitoria ternatea и Andrographis paniculata

Aparajita ( Clitoria ternatea Linn.), a medicinal plant belonging to the Fabaceae family, is well recognized in Ayurveda for its memory-enhancing properties. It is traditionally used in the treatment of various ailments, including diabetes, dropsy, mucous disorders, skin diseases, sore throat, tumors, inflammation, burning sensation, and urogenital disorders. Andrographis paniculata (Burm. f.) Wall. ex Nees, a member of the Acanthaceae family, is another important medicinal plant widely utilized in the Indian traditional system of medicine. Commonly known as Kalmegh or the “King of Bitters,” it is extensively used for the treatment of fever, cold, blood purification, and various infectious diseases, including malaria, dysentery, and diarrhea.The present investigation aimed to isolate major phytochemicals from these plants. Plant materials were extracted using different solvents, and the extracts were subjected to chromatographic techniques for the isolation of major compounds from Clitoria ternatea and Andrographis paniculata . The isolated compounds were further purified through repeated column chromatography and crystallization using suitable solvents. Structural characterization was carried out using nuclear magnetic resonance (NMR) and mass spectrometry. The identity of the isolated compounds was confirmed based on spectral data and comparison with published literature.The compounds isolated in this study may serve as potential candidates for further development in herbal medicine and pharmacological research.